Homeopatia na oncologia pediátrica: é possível? Uma série de casos / Homeopathy in oncology pediatric: is it possible? case series

A Homeopatia é uma das ciências médicas complementares mais utilizadas para pacientes com Câncer, sendo também utilizada durante o tratamento de crianças com a referida moléstia, havendo relato e debate de seu uso na literatura médica. Visando construir o conhecimento e dividir experiências, relatamos seis casos de crianças e adolescentes com câncer, para os quais realizamos tratamento homeopático, em nossa experiência na cidade de São Paulo. Além da diversidade de sexos e idade, os casos apresentam diagnósticos oncológicos diferentes, bem como momentos diferentes no tratamento, sendo curativo ou paliativo, e os medicamentos homeopáticos, baseados tanto na totalidade sintomática característica quanto no modo reacional para cada indivíduo, puderam ser utilizados para todos com satisfação de famílias e pacientes, mesmo quando o desfecho letal foi a via final no estado paliativo. Assim, a Homeopatia pode também ser prescrita para os casos oncológicos infantis como terapia complementar ao tratamento convencional, sendo a pesquisa neste campo vasta e possível.

Homeopathy is one of the most used complementary medical sciences for cancer patients, and is also used duringtreatment of children with the aforementioned disease, with reports and debate of its use in medical literature. Aiming to build knowledge and sharing experiences, we report six cases of children and adolescents with cancer, for which we carry out homeopathic treatment, in our experience in the city of São Paulo. In addition to the diversity of sexes and age, the cases present different oncological diagnoses, as well as as different moments in the treatment, being curative or palliative, and homeopathic medicines, based both on symptomatic totality characteristic and in the reactional mode for each individual, could be used for everyone with the satisfaction of families and patients, even when the lethal outcome was the final route in the palliative state. Therefore, Homeopathy can also be prescribed for oncological cases children as complementary therapy to conventional treatment, research in this field is vast and possible.

Silicea terra200cH evaluated by two different spectroscopy methods: a pilot study

Spectroscopy has been shown to bea useful method to study the physicochemical properties of homeopathic preparations. Aim: In this pilot study, we comparedtwo methods (photon scattering and visible-light spectroscopy) in the physicalevaluation of Silicea terra200cH. Methodology: Italian test: Two sampleshave been examinedand compared: Silicea terra200cH and Sac lac200cH, both preparedin water solution, diluted and succussed according to German Homeopathic Pharmacopoeia(Cemon Lab, Italy).Lactose was includedbecause the first 3 potencies of Silicea terraaremadeby trituration in lactosepowder.Measurements were made using an innovative Charge-Coupled Device (CCD) camera developedby Daniele Gullà, called MIRA/CORA(proprietary name). Slight variations in chrominance and luminance due to micro-vibrational 3D phenomenawere analyzed.Allmeasurements have been performed in a dark room at a constant temperature of 22°C +/-0,2°C usingafilter with very narrow spectral bands (10 nm).The measurements have been repeated three times on both Silicea terra200cH and Sac lac200cHwithin a few minutes aftereach other.Brazilian test: In the second test, performed in Brazil, variations in absorbance were used to identify Silicea terra200cH compared with Sac lac200cH andcompared withanother control solution of non-succussed 30% alcohol, using six solvatochromic dyes, following the method developed by Cartwright [1,2]. Both homeopathic samples were imported from Italy(the same sample bottles used in the Italian test),in Brazil they have beendiluted 1:100 in 30% hydro-alcoholic solution, and submitted to 100 succussions using an automatic mechanical arm (Denise, AUTIC, Brazil) prior to being tested. Samples were inserted into dyes solutions and evaluated by visible spectroscopy (FEMTO Spectrophotometer, Brazil). Dyes were prepared in ethanol P.A., according to previous established methods [3]. Three series in triplicate were performed and the results were analyzed by ANOVA / Tukey, comparing both samples and the unsuccussed 30% hydroalcoholic control solution.Results: Italian test: Measurements of the mean entropy of the signals, statistically elaborated with T Student test,yielded a two tailed p value < 0.05, where the entropy of the signal recorded from the Silicea terra200cHsample was statistically lower than the 200cH Sac lacsample.Brazilian test: Among all tested dyes, only BDN(4-(Bis-(4-(dimethylamino)-phenyl)methylene)-1(4H)-naphthalenone) showed aninteraction with Silicea terra200cH, reproducing the conclusions obtained in [3].Conclusions: Two different spectroscopic methods were able to show signal differences betweenSilicea terra200cH andSac lac200cH, suggesting that changes in solvent organization could be involved in the homeopathic signaling process, along withchanges in dipole moments of solvent and dyes. The results are potentially in line witha recent publishedpaper [4], that supportsthe propositionthatthe lower entropy of the verum signal compared with controls could beexplained by increased coherent vibrations of the verum sample, as theoretically explained in previous literature [5].

Feasibility in seed germination of Hypericum perforatum L. submitted at different temperatures and treatments with high dilutions

Background Hypericum perforatum is used as a medicinal plant, mostly in antidepressant treatment. With endogenous and exogenous dormancy, more studies about the germination of the seeds are necessary. Aim: To evaluate the effect of temperature and of preparations of high dilutions on the germination of seeds of Hypericum perforatum. Methods Three bioassays were carried out in chambers of germination, using a completely randomized experimental design and in duplicate. In the first bioassay, of temperatures of 20, 25 and 30 ºC was evaluated, with 20 replicates and 50 seeds in each replicate. In the second, the effect of high dilutions (Kali carbonicum, Natrum muriaticum, Phosphorus and Silicea terra in 12cH) using 4 replicates with 50 seeds each. In the third, Kali carbonicum was tested at 6, 12, 20, 30 cH with 50 seeds and 4 replicates. The percentage of germination, germination rate index (GRI), average germination time (AGT) and seedlings with cotyledons. The data were analyzed through the R software at a 5% significance. Results At the temperature of 25 °C, 63% of the seeds germinated while at the temperatures of 20 and 30 °C the percentage was 26% and 18%, respectively. In seeds treated with Kali carbonicum 12cH the germination rate increased significantly in relation to the control group. Kali carbonicum 6cH increased the GRI of the seeds, while at 20cH, it increased the AGT, showing delay in germination. Conclusion The use of the Kali carbonicum assists in the breakage of dormancy and average time of germination in Hypericum perforatum seeds. (AU)

Management of early years of simple and mucopurulent chronic bronchitis with pre-defined Homoeopathic medicines ­ a Prospective Observational Study with 2-Years Follow-Up

Background Simple and mucopurulent chronic bronchitis (SMCB) is characterized by recurrent mucoid or mucopurulent expectoration in absence of localized suppurative disease. This observational open label study was undertaken to evaluate the effects of homeopathic medicine in SMCB. Methods 1902 patients were screened from 07 centres out of which 1305 were excluded. 597 patients were enrolled as per the inclusion and exclusion criteria. A total of 14 pre-defined homeopathic medicines were shortlisted for prescription after repertorizing the pathological symptoms of SMCB. Outcomes were assessed through chronic bronchitis symptom scale (CBSS) and FEV1/ FVC ratio with spirometry for over a period of two years. Appearance of any change (relief/ worse)/ status quo was immediately followed by placebo/ change in dilution/ change in remedy. Statistical analysis was done using SPSS version 20. Results: 532 patients were analyzed based on the intention to treat principle using last observation carry forward method. Mean CBS score reduced from 29.86±4.5 at baseline to 12.33±7.6 at completion of 2 years. Repeated measures ANOVA, at time points 0 (baseline), 3, 6, 9, 12 ,15, 18, 21 and 24 months, showed significant reduction in CBS scores [Wilk's Lambda 0.104, F=564, df 524; p=00001]. The FEV1 and FEV1/FVC was maintained within normal limits. 86% prescriptions included Lycopodium, Arsenicum album, Pulsatilla, Phosphorus, Stannum metallicum, Calcarea carbonica, Silicea, Bryonia alba. Conclusion: The result suggests effectiveness of homeopathic treatment in early years of SCMB patients. Controlled trials are warranted. (AU)

Relato de um caso de tratamento homeopático de portadora de gastroparesia diabética / Report of a case of homeopathic treatment of patients with diabetic gastroparesis

O presente trabalho consiste num estudo descritivo baseado em coleta e análise de dados de prontuário. Trata do caso de uma paciente diabética, com gastroparesia internada no Hospital Público Regional de Betim, Minas Gerais. Reconheceu-se, na base da doença, específico desequilíbrio de saúde, susceptível de ser tratado com Silicea terra. Recorreu-se a memória sintética experimental, que compreende timidez, sensibilidade à contradição, conscienciosidade, antecipação, transtornos por separação, acne e intolerância a corpos estranhos. Após dose única do medicamento na diluição 30cH, observaram-se rápida melhora de sensação de doença, processos exonerativos e exercícios de vitalidade. Apesar do ambiente hospitalar enfatizar a paliação da doença, consegue-se demonstrar a efetividade da homeopatia neste nível de atenção médica e de ensino, auxiliando na simplificação terapêutica. Conclui-se que a homeopatia pode integrar o conjunto de alternativas médicas disponíveis para a atenção hospitalar, com finalidades de ensino, e pode auxiliar na simplificação terapêutica, a partir da cura de sensação de doença.

The present is a descriptive study based on collection and analysis of data from medical records. It concerns the case of a diabetic patient with gastroparesis admitted to Public Regional Hospital, Betim, Minas Gerais, Brazil. At the bottom of her disease we detected a specific health imbalance likely to respond to Silicea terra. We had resource to an experimental synthetic memory comprising: timidity; sensitivity to contradiction; consciousness; anticipation; ailments from separation; acne; and intolerance to foreign bodies. Following a single dose of Sil 30cH the patient exhibited fast improvement of her feeling of illness, exoneration symptoms and exercise of vitality. While the hospital setting prioritized the palliation of disease, the effectiveness of homeopathy also in this level of medical care and teaching might be demonstrated, contributing to the simplification of treatment. We conclude that homeopathy can be included among the medical alternatives available for inpatient care and teaching, and that it might contribute to the simplification of treatments based on the cure of the feeling of illness.

Free water molecules and hydrogen bonding form the basis of variation in homeopathic potencies as revealed by vibrational spectroscopy

Using Fourier Transform Infrared spectroscopy (FTIR) we have demonstrated that homeopathic potencies of Natrum mur, Cantharis, Nux vomica and Sulphur show differences with respect to the number of free water molecules and strength of hydrogen bonding. The purpose of the present study is to confirm this phenomenon in three potencies of two more drugs Calcarea carb and Silicea. Design: The potencies used for each of the two drugs were 30cH, 200cH and 1000cH. The control was 90% ethanol as also the potentized drugs. The control, as well as the potencies, were diluted with distilled water to reduce the level of ethanol to 0.03 molar fraction in each of them. FTIR spectra of all the potentized drugs, control and sterile distilled water (reference water) were taken in the wave number region of 4000-2800 cm-1. The full width at half maximum (fwhm) of OH band was measured for each spectrum. The width was divided into two in the middle. The difference spectrum (absorbance of drug solution - absorbance of reference water) for each potency and the control was obtained after normalization of the spectrum at 3410 cm-1. One difference spectrum so obtained for a potency was subtracted from another to find out if there is a difference between two different potencies. Results: The half width half maximum (hwhm) in both the high and low-frequency sides of the OH band is far less narrow in potencies than in the control as compared to that in water. The difference spectra for different potencies show different levels of fall in intensity at the wave number region of dip at 3630 cm-1...

Personalidad sobreadaptada y homeopatía / Personality sobreadaptada and homeopathy

El presente trabajo está destinado a describir una estructura de personalidad que se observa cada vez con mayor frecuencia, muy favorecida por la actual “cultura del éxito”. Quienes la presentan son personas que sostienen un excesivo ajustea la realidad exterior y a sus exigencias, disociando necesidades y posibilidades emocionales y corporales. Se establece la relación del cuadro psicopatológico con algunos remedios homeopáticos.

This paper is intended to describe a personality structure that is observed with increasing frequency, favored by the current "culture of success". Those who have are people who argue overshootingto external reality and demands decoupling emotional and physical needs and possibilities. The relationship of psychopathology with some homeopathic remedies set.

Las bases científicas de la homeopatía / The scientific basis of homeopathy

A través de un recorrido por los principios de la Homeopatía y la evolución de sus ideas es posible delimitar las líneas de investigación que podrían desarrollarse para responder las dudas e interrogantes que surgen de la aplicación de esta disciplina,situada entre las ciencias médicas, humanas, biológicas y físicas.A continuación se presenta el resumen de diversas investigaciones que han comprobado, por ejemplo, que los medicamentos homeopáticos sí actúan en células, modelos animales y seres humanos, aunque no se ha logrado explicarcómo; además, se pone de manifiesto que los criterios para evaluar no pueden ser idénticos a los que se emplean en la farmacología clásica, si bien existe cierta similitud.Se concluye que a pesar de que hay demasiados aspectos de la Homeopatía que siguen sin tener una explicación coherente en términos científicos clásicos, no deben rechazarse sin miramientos, sino estudiarse.

Through a tour of the principles of homeopathy and the evolution of his ideas is possible to delineate the lines of research that could be developed to answer the doubts and questions that arise from the application of this discipline, between the medical and social sciences, biological and physical.The summary of several studies that have found, for example is presented, that homeopathic medicines do act on cells, animal models and humans, but has not been able to explainhow; moreover, shows that the criteria for evaluating may not be identical to those used in classical pharmacology, while there is some similarity.We conclude that although there are too many aspects of homeopathy that still lack a coherent explanation in classical scientific terms, should not be rejected without consideration, but studied.

Preparados homeopáticos e ambiente de cultivo na produção e rendimento de quercetina em carqueja [Baccharis trimera (Less) DC. ] / Homeopathic preparations and crop environments through production and yield of quercetin on carqueja plants [Baccharis trimera (Less) DC. ]

A carqueja (Baccharis trimera) é uma espécie da família Asteraceae muito utilizada na medicina popular por apresentar várias atividades biológicas relacionadas à seus metabólitos secundários, entre eles os flavonoides. Este experimento teve como objetivo avaliar os efeitos de preparados homeopáticos e do ambiente de cultivo na produção e rendimento de flavonoides totais expressos em quercetina por plantas de carqueja. Foi adotado o esquema fatorial 6 x 2 no delineamento inteiramente casualisado, sendo 5 tratamentos homeopáticos: Silicea CH6, CH12, CH30, D7 e Equisetum D7 e controle (etanol 70%) x 2 ambientes de cultivo: estufa e tela de sombreamento 50%, com 4 repetições, totalizando 48 unidades experimentais. Os tratamentos homeopáticos foram aplicados na concentração de 25 gotas/500 mL de água destilada usando borrifadores manuais. Cada planta recebeu 10 mL da solução por aplicação, via foliar. As aplicações foram realizadas sempre pela manha, três vezes por semana, em dias alternados, durante dois meses (27/07/2010 a 27/09/2010). A interação entre os fatores, assim como os fatores independentes foram comparados pelo teste Tukey a 5% de probabilidade. O efeito dos preparados homeopáticos e dos dois ambientes de cultivo em plantas de carqueja foi avaliado pelas variáveis: massa fresca (MFPA), massa seca (MSPA) e teor de quercetina (QCT) na parte aérea das plantas. As variáveis MFPA e QCT foram influenciadas pelos ambientes de cultivo, pelos preparados homeopáticos e pela interação entre os dois fatores. A variável MSPA foi influenciada apenas pela interação dos fatores. Plantas cultivadas em ambiente com 50% de sombreamento associadas à aplicação dos preparados homeopáti-cos Silicea CH6 e D7, apresentaram maior rendimento em querceti-na. Plantas cultivadas na estufa associadas à aplicação do Equisetum D7 apresentaram menor rendimento em quercetina.

The carqueja plant (Baccharis trimera) is a specie of the family Asteraceae widely used in folk medicine for presenting various biological activities, due to the high content of secondary metabolites, including flavonoids. The objective of this study was to evaluate the effect of homeopathic preparations and crop environments through production and yield of quercetina on carqueja plants. The experiment was a factorial scheme (6X2) on completely randomized design with 5 homeopathic treatments: Silicea CH6, CH12, CH30, D7 and Equisetum D7 e control (70% ethanol) x 2 crop environments: greenhouse and shade 50% and 4 replicates, totaling 48 experimental units. The treatments were applied at concentration of 25 drops/500 mL of distilled water using hand sprayers. Each plant received 10 mL via leaves. The prepara-tions were sprayed always on mornings, three times a week on alternate days during two months (27/09/2010 to 27/11/2010). The interaction between the factors as well as the independents factors were compared by the Tukey test at 5% probability. The effect of homeopathic preparations and the two crop environments on carqueja plants were evaluated through the variables: fresh matter of aerial part (FMAP), dry matter of aerial part (DMAP) and flavonoids content (QCT). The variables FMAP and QCT were significantly influenced by the crop environments, the preparations and interaction between the two factors. The DMAP was only influenced by the interaction of the two factors. The 50% shade environment associated with Silicea CH6 or D7 increased yield of quercetin. The greenhouse environment associated with Equisetum D7 decreased yield of quercetin.

Suplementação de vacas leiteiras com homeopatia: desempenho e digestibilidade / Supplementation of dairy cows with homeopathy: performance and digestibility

Avaliou-se o efeito da suplementação de uma combinação homeopática sobre o desempenho e a digestibilidade de nutrientes em vacas leiteiras. Trinta e duas vacas Holandesas foram blocadas em pares e aleatoriamente alocadas a um de dois tratamentos por 63 dias, posterior a um período de padronização de 14 dias. Variáveis mensuradas no final da padronização ajustaram medidas semanais da mesma variável no modelo de análise estatística. Os tratamentos foram: Suplementação diária com 150 gramas de uma combinação homeopática (Hypothalamus, 10-30; Colibacilinum, 10-30; Streptococus Beta Hemolyticum, 10-60; Streptococus Uberis, 10-60; Phytolacca, 10-60; Calcium Phosphoricum, 10-30; Natrum Muriaticum, 10-60; Urtica Urens, 10-30; Silicea Terra, 10-400) em veículo mineral, ou 150 gramas do mesmo veículo mineral (controle). A suplementação com homeopatia aumentou o teor de proteína no leite de 3,09 para 3,19 por cento (P=0,01) e tendeu a aumentar a secreção diária de proteína de 0,737 para 0,776kg (P=0,10). A queda na digestibilidade da fibra e da matéria orgânica (P=0,10), e a similaridade na relação entre alantoína e creatinina na urina (P=0,32), sugerem que houve aumento na eficiência de síntese de proteína microbiana no rúmen. Apesar de o mecanismo não ter sido elucidado, a combinação homeopática aumentou o teor de proteína do leite.

The effect of supplementing a homeopathic combination on dairy cow performance and nutrient digestibility was evaluated. Thirty-two Holstein cows were paired blocked and randomly assigned to one of two treatments for 63 days, following a 14-day standardization period. Variables measured at the end of the standardization period adjusted weekly measurements of the same variable in the statistical analysis model. Treatments were: Daily supplementation of 150 grams of a homeopathic combination (Hypothalamus, 10-30; Colibacilinum, 10-30; Streptococcus Beta Hemolyticum, 10-60, Streptococcus Uberis, 10-60; Phytolacca, 10-60; Calcium Phosphoricum, 10-30; Natrum Muriaticum, 10-60; Urtica Urens, 10-30, Silicea Terra, 10-400) in mineral vehicle, or 150 grams of the same mineral vehicle (Control). Supplementation with homeopathy increased milk protein content from 3.09 to 3.19 percent (P=0.01) and tended to increase the daily secretion of protein from 0.737 to 0.776kg (P=0.10). The trend for decreased fiber and organic matter digestibilities (P=0.10), and the similar allantoin to creatinine ratio in urine (P=0.32), suggests that there was an increase in the efficiency of microbial protein synthesis in the rumen. Although the mechanism could not be elucidated, the homeopathic combination increased milk protein content.

Tratamento homeopático na tiroidite autoimune: relato de caso / Homeopathic treatment of autoimmune thyroiditis: case-report

A prescrição do medicamento constitucional - Silicea terra - e de organoterápico de tireoides num caso de tireoidite autoimune resultou na normalização gradual dos valores plasmáticos dos hormônios tireóideos e hipofisários, assim como na negativação dos autoanticorpos no prazo de nove meses. O caso foi acompanhado durante um ano e meio e permanece estável. Discute-se o ordenamento em que se realiza a cura de doenças que acometem o sistema imune versus as leis de Hering.

Prescription of constitutional medicine - Silicea terra - and organotherapy prepared from thyroid to a case of autoimmune thyroiditis resulted in gradual normalization of serum values of thyroid and hypophysis hormones and full disappearance of autoantibodies in nine months. This case was followed-up for one year and a half and it remains stable. The order in which cure is processed in diseases involving the immune system is discussed against Hering’s laws.

Liquen plano erosivo vulvar asociado a granuloma de sílice: reporte de un caso / Vulvar erosive lichen planus associated with silica granulom: case report

Se presenta el caso de una paciente mujer de 52 años con prurito intenso y dolor en vulva con tres años de evolución, quien usó varios tratamientos tópicos como corticoides y talco para calmar el prurito. El estudio histopatológico reveló dos patrones de infiltrado, el primero, un infiltrado liquenoide con atrofia de la epidermis compatible con liquen plano erosivo vulvar, y el segundo, un infiltrado profundo y organizado en granulomas sin necrosis gaseosa, con múltiples células gigantes a cuerpo extraño y con un material cristalino en su interior que a la microscopía de luz polarizada se reveló como espículas brillantes birrefringentes compatibles con silice. Se presenta el caso por ser la primera descripción de asociación entre liquen plano erosivo vulvar y granuloma a sílice.

We present the case of 52 year old women who had a three year history of severe itching and pain in vulva, for which she used several topical treatments such as corticosteroids and tale to soothe the itching. The histopathology study revealed two patterns of infiltration, the first, a lichenoid infiltrate with atrophy of the epidermis consistent with vulvar erosive lichen planus, and the second, a deep infiltrate organized in granulomas without caseous necrosis, with multiple foreign body giant cells and a crystalline material inside, which in polarized light microscopy revealed itself as bright birefringent spicules, compatible with silica. We present this caseas the first description of an association between vulvar erosive lichen planus and silica granuloma.

Silicea: medicamento de gran utilidad en el manejo de úlceras crónicas de piel / Silicea: a drug of great uility in the managment of chronic skin ulcers

Se presentan tres pacientes con úlcera en piel de diferentes etiologías, las cuales cicatrizaron con el uso de Silicea 30CH. Además, se hace una revisión bibliográfica sobre las úlceras en piel, su etiología y su tratamiento tanto alopático como homeopático

Silicia / Silicea

El presente trabajo estudia a SILICEA con respecto a las distintas etapas de la vida como neonato, lactante, niñez y adolescencia. Trata de resumir cómo pueden reconocerse en las distintas etapas de la vida y respalda el conocimiento de Materia Médica con búsquedas de síntomas en el repertorio. Además aproxima algunos medicamentos con los que pueden establecerse diferencias a partir de su tropismo orgánico, sin por eso dejar de considerar los síntomas mentales como los guías de cualquier diagnóstico homeopático

Tres historias clínicas, tres enseñanzas doctrinarias / Three clinical records, three doctrinal teaching

La descripción de tres historias clínicas homeopáticas, da base a corroboraciones doctrinarias, como modo de aunar la práctica a la teoría homeopática

Estudo experimental da resposta terapêutica em abcessos sub-cutâneos provocados por injeçäo de terebintina em ratos / Experimental research of the therapeutical response in subcutaneous abscesses in mice caused by ingestion of tupentine

Os autores estudaram experimentalmente a açäo antiinflamatória de Belladonna e Silicea em ratos nos quais se provocou abcesso subcutâneo com injeçäo de terebintina.

Reumatismo poliarticular agudo o fiebre reumatica / Polyarticular rheumatism or rheumatic fever

Se trata de un caso de reumatismo poliarticular agudo en el cual es utilizado un modelo particular de jerarquización, el cual difiere del clásico en que se da preponderancia a la causalidad, al diagnóstico nosológico adaptado a la terminología del repertorio y a la modalización de los particulares según el esquema de Hering. Los mentales antiguos no son tomados en cuenta excepto que se hallen exacerbados (lo mismo para los generales). El medicamento curativo fue Spongia, el cual cubría los síntomas más importantes característicos y poseía el tropismo lesional